Stem Cell & Regenerative Medicine

Senescence Cells

Cellular Senescence refers to the basically irreversible arrest of cell proliferation (growth) that happens once cells expertise doubtless oncogenic stress .The permanency of the senescence growth arrest enforces the concept that the senescence response evolved a minimum of partly to suppress the event of cancer . The senescence arrest is taken into account irreversible as a result of no famous physiological stimuli will stimulate old cells to enter the cell cycle.  Senescence cell response is well known as a potent neoplasm restrictive mechanism. However, recent proof strengthens the concept that it conjointly drives chronic pathologically, presumably by promoting chronic inflammation. Thus, the senescence response is also the results of antagonistically pleiotropic sequence action..